T-Cell Lymphoma is a type of non-Hodgkin lymphoma (NHL). It can develop in the lymph nodes, bone marrow, or other organs. This type of lymphoma can be aggressive or indolent. It can cause infections or interfere with the body’s ability to make blood cells, resulting in fatigue and bleeding. In many cases, doctors can make a diagnosis of cutaneous non-Hodgkin lymphoma from blood tests and other information about the health. Occasionally, a biopsy of a lymph node is necessary.
The doctor may also use bone marrow aspiration and biopsy to check if cancer has spread to the bones. The biopsy removes a small piece of bone and solid marrow from the back, which is examined under a microscope to look for signs of lymphoma. CTCL is a type of non-Hodgkin lymphoma that develops from white blood cells called lymphocytes. The lymphocytes travel through the body and help fight infection. T-Cell Lymphoma has several treatment options, depending on the type of lymphoma and its stage. Typically, the goal of treatment is to reduce tumors and slow their growth. The doctor will use tests to diagnose the type of non-Hodgkin lymphoma patients have, such as a blood test that measures the T-cell count. The doctor will also go through other tests to find out how advanced the cancer is and what treatment option might be best for them. For cutaneous non-Hodgkin lymphoma, which is the most common subtype, patients may be treated with chemo regimens. The treatments for non-Hodgkin lymphoma depend on the type of lymphoma patients have and where it is found in the body. A form of gene cell therapy known as CAR-T Cell Therapy uses T cells to attack cancer cells. Treatment for non-Hodgkin lymphoma that affect the skin usually includes a variety of medicines to treat the immune system and control cancer cells. If the non-Hodgkin lymphoma has spread to the bone marrow, patients might have a stem cell transplant. These transplants might include autologous stem cells or bone marrow from a donor. Non-Hodgkin lymphoma make up less than 15 percent of non-Hodgkin lymphomas in the United States. They can develop in the lymph nodes or other parts of the body - for example, the liver, bone marrow, or gut. T cells are white blood cells that help control the immune system and attack germs, abnormal cells, and viruses. In a healthy body, they die when their job is done, and new ones are made to replace them. If the T-Cell Lymphoma hasn't spread to the bone marrow, chemotherapy (usually a combination of cyclophosphamide, doxorubicin, vincristine, and prednisone) might be given. Patients might also be a candidate for newer chemo drugs or targeted therapy medicines, such as bortezomib or brentuximab vedotin. But in T-Cell Lymphoma, the body makes too many T cells and they don't die, so they continue to grow and divide abnormally. They can grow into large tumors or can spread to other areas of the body. Some people who have this type of lymphoma are infected with a virus called HTLV-1. They can get it through sexual contact, exposure to contaminated blood, or breastfeeding. This virus is linked to a number of different types of cancer. It's also believed to be a risk factor for adult non-Hodgkin lymphoma. Source Link: https://www.globenewswire.com/en/news-release/2021/12/20/2355334/0/en/Global-T-cell-Lymphoma-Market-to-Surpass-US-2-495-4-Million-by-2028-Says-Coherent-Market-Insights-CMI.html
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